Reply to Weird problem with s4

For some reason sometimes when I load up T2 my s4 doesn't respond. I know I installed the drivers correctly and when i power up the s4 everything is fine, the device is recognized and all that jazz. The only way I can get the s4 to control TP2 is to restart my computer. It worked fine in the kontrol s4 software but not with TP2. It's starting to become a hassle.. Any idea on what could be causing this?