Reply to Partitions on Mac?

Hey All! So I have a brand new 15" MBP coming in the mail. 500GB HDD, 4GB RAM, quad core @ 2.2 Ghz. I was wondering what you guys thought about setting up a separate partition for DJing related stuff. Has anyone here done this? If so, for what reason and what were the results? Anybody have any objections of why this is a bad idea? I've never tried so just wanna make sure I'm not wasting my time and effort because it might now even make a difference. Thanks guys!