Reply to Looking for a movie/TV quote....

Ey guys, I just vaguely remembered a hilarious scene from a movie or tv show - and I can't for the hell of it figure out where it's from (and knowing myself this will drive me insane until I've found the answer). And as I can't remember the exact wording google isn't of much help. So maybe someone here can help me out.

It was some dude who believes there is some big conspiracy going on against him (or something of that sort) and when he's asked who is plotting against him by a friend, he answers something like "the universe, the universe is trying to kill me". Could have been Jesse Pinkman in Breaking Bad, but I believe it was a character even more hysterical.

Anybody got an idea?