Reply to Serato Itch and external soundcard?

I googled all over the place to try to find the answer to this question, but is it possible to use an external soundcard (i.e: Presonus Firebox) with Itch?.

As in, using a VCI-300 to control all the cue/play/scratch/sampling, but routing the decks within Itch through 2 separate channels via external soundcard so that I can use an actual DJ mixer instead of the VCI-300's onboard mixer?.

Many thanks in advance