Reply to becoming very aggravated with my cue master

OK so before i get flamed i read the entiere cue mast thread and cant seem to find something that will help diagnose my problem.

I upload the TSI in the pref. window but when i do so it completely disables my S4! i cant even use the play button. also, i cannot use the midi fighter to play sync etc, only the super knobs work... someone help please?