Reply to Keeping HDD up to date

I currently have a 250 GB Hard drive(500GB Lacie with 2 partitions) formatted to FAT 32 with all my music. Eventually I would like to solely play off this drive but as of now its a back up for my music on my standard C: drive. I'm looking for any program or application that would essentially update my music folder (delete, move, add, etc) on my Lacie HDD to mimic the music folder on my C: drive as doing this manually can be quite tedious. Any advice or suggestions?