Reply to Running Guitar Through Computer

Hey everyone I am looking into making Radiohead, Aphex Twin, Muse esque sounds. I have a Fender Strat and gibson Les Paul with 2011 MBP 17". I plan to run through the program Max/Msp. I have a large pedal board to create many sounds and I run it through a Mesa Boogie Dual Rectifier. Can I get recommendations on the sound card I should upgrade to, to have no signal loss in my expensive gear. I also need recommendations on the interface I should use to get my guitar to my computer. Lastly I need thoughts on a signal chain into the computer and out. I don't have an extremely large budget but if you recommend something very expensive justify why I shouldn't get something cheaper. I want to thank everyone in advance!!